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1.Yang, D. et al. Lineage tracing reveals the phylodynamics, plasticity, and paths of tumor evolution. Cell 185, 1905-1923.e25 (2022).
2.Wang, C. et al. Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy. Nat Commun 13, 1969 (2022).
3.Thorne, L. G. et al. Evolution of enhanced innate immune evasion by SARS-CoV-2. Nature 602, 487–495 (2022).
4.Su-Feher, L. et al. Single cell enhancer activity distinguishes GABAergic and cholinergic lineages in embryonic mouse basal ganglia. Proceedings of the National Academy of Sciences 119, e2108760119 (2022).
5.Servellita, V. et al. Predominance of antibody-resistant SARS-CoV-2 variants in vaccine breakthrough cases from the San Francisco Bay Area, California. Nat Microbiol 7, 277–288 (2022).
6.Replogle, J. M. et al. Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors. 2022.07.13.499814 Preprint at https://doi.org/10.1101/2022.07.13.499814 (2022).
7.Ranade, S. S. et al. Single Cell Epigenetics Reveal Cell-Cell Communication Networks in Normal and Abnormal Cardiac Morphogenesis. 2022.07.25.501458 Preprint at https://doi.org/10.1101/2022.07.25.501458 (2022).
8.Perlaza, K., Mirvis, M., Ishikawa, H. & Marshall, W. The short flagella 1 (SHF1) gene in Chlamydomonas encodes a Crescerin TOG-domain protein required for late stages of flagellar growth. MBoC 33, ar12 (2022).
9.Neely, J. et al. Multi-Modal Single-Cell Sequencing Identifies Cellular Immunophenotypes Associated With Juvenile Dermatomyositis Disease Activity. Front Immunol 13, 902232 (2022).
10.Murrow, L. M. et al. Mapping hormone-regulated cell-cell interaction networks in the human breast at single-cell resolution. Cell Systems (2022) doi:10.1016/j.cels.2022.06.005.
11.Majd, H. et al. hPSC-Derived Enteric Ganglioids Model Human ENS Development and Function. 2022.01.04.474746 Preprint at https://doi.org/10.1101/2022.01.04.474746 (2022).
12.Le Duc, D. et al. Genomic basis for skin phenotype and cold adaptation in the extinct Steller’s sea cow. Science Advances 8, eabl6496 (2022).
13.Kostyrko, K. et al. UHRF1 is a mediator of KRAS driven oncogenesis in lung adenocarcinoma. https://www.researchsquare.com/article/rs-1651106/v1 (2022) doi:10.21203/rs.3.rs-1651106/v1.
14.Kiefer, L. et al. Cohesin erases genomic-proximity biases to drive stochastic Protocadherin expression for proper neural wiring. 2022.03.09.483674 Preprint at https://doi.org/10.1101/2022.03.09.483674 (2022).
15.Kersten, K. et al. Spatiotemporal co-dependency between macrophages and exhausted CD8+ T cells in cancer. Cancer Cell 40, 624-638.e9 (2022).
16.Granados, A. C. et al. Longitudinal comparison of the developing gut virome in infants and their mothers. 2022.05.13.491764 Preprint at https://doi.org/10.1101/2022.05.13.491764 (2022).
17.Fasching, C. L. et al. COVID-19 Variant Detection with a High-Fidelity CRISPR-Cas12 Enzyme. Journal of Clinical Microbiology 60, e00261-22 (2022).
18.Choudhury, A. et al. Meningioma DNA methylation groups identify biological drivers and therapeutic vulnerabilities. Nat Genet 54, 649–659 (2022).
19.Chinn, A. M. et al. PDE4B Is a Homeostatic Regulator of Cyclic AMP in Dendritic Cells. Front Pharmacol 13, 833832 (2022).
20.Chaturvedi, S. et al. Disrupting autorepression circuitry generates “open-loop lethality” to yield escape-resistant antiviral agents. Cell 185, 2086-2102.e22 (2022).
21.Zalocusky, K. A. et al. Neuronal ApoE upregulates MHC-I expression to drive selective neurodegeneration in Alzheimer’s disease. Nat Neurosci 24, 786–798 (2021).
22.Taubes, A. et al. Experimental and real-world evidence supporting the computational repurposing of bumetanide for APOE4-related Alzheimer’s disease. Nat Aging 1, 932–947 (2021).
23.Redmond, S. A. et al. Single-cell analysis of the ventricular-subventricular zone reveals signatures of dorsal and ventral adult neurogenic lineages. 2021.02.10.430525 Preprint at https://doi.org/10.1101/2021.02.10.430525 (2021).
24.Pedersen, M. W. et al. Environmental genomics of Late Pleistocene black bears and giant short-faced bears. Current Biology 31, 2728-2736.e8 (2021).
25.Ng, D. L. et al. A diagnostic host response biosignature for COVID-19 from RNA profiling of nasal swabs and blood. Science Advances 7, eabe5984 (2021).
26.McGinnis, C. S. et al. No detectable alloreactive transcriptional responses under standard sample preparation conditions during donor-multiplexed single-cell RNA sequencing of peripheral blood mononuclear cells. BMC Biology 19, 10 (2021).
27.Lee, Y. et al. XYZeq: Spatially resolved single-cell RNA sequencing reveals expression heterogeneity in the tumor microenvironment. Science Advances 7, eabg4755 (2021).
28.Laufer, B. I. et al. Multi-omic brain and behavioral correlates of cell-free fetal DNA methylation in macaque maternal obesity models. 2021.08.27.457952 Preprint at https://doi.org/10.1101/2021.08.27.457952 (2021).
29.Krishna, S. et al. Glioblastoma remodeling of neural circuits in the human brain decreases survival. 2021.02.18.431915 Preprint at https://doi.org/10.1101/2021.02.18.431915 (2021).
30.Kathiriya, I. S. et al. Modeling Human TBX5 Haploinsufficiency Predicts Regulatory Networks for Congenital Heart Disease. Developmental Cell 56, 292-309.e9 (2021).
31.Hwang, B. et al. SCITO-seq: single-cell combinatorial indexed cytometry sequencing. Nat Methods 18, 903–911 (2021).
32.Hussmann, J. A. et al. Mapping the genetic landscape of DNA double-strand break repair. Cell 184, 5653-5669.e25 (2021).
33.Huang, L. et al. Commitment and oncogene-induced plasticity of human stem cell-derived pancreatic acinar and ductal organoids. Cell Stem Cell 28, 1090-1104.e6 (2021).
34.Holden, S. S. et al. Complement factor C1q mediates sleep spindle loss and epileptic spikes after mild brain injury. Science 373, eabj2685 (2021).
35.Ho, B. et al. Gut Metabolites Are More Predictive of Disease and Cohoused States than Gut Bacterial Features in a Polycystic Ovary Syndrome-Like Mouse Model. mSystems 6, e01149-20 (2021).
36.Hardigan, M. A. et al. Unraveling the Complex Hybrid Ancestry and Domestication History of Cultivated Strawberry. Molecular Biology and Evolution 38, 2285–2305 (2021).
37.Han, R. T. et al. Interleukin-33 coordinates a microglial phagocytic response and limits corticothalamic excitability and seizure susceptibility. 2021.08.05.455250 Preprint at https://doi.org/10.1101/2021.08.05.455250 (2021).
38.Haderk, F. et al. A focal adhesion kinase-YAP signaling axis drives drug tolerant persister cells and residual disease in lung cancer. 2021.10.23.465573 Preprint at https://doi.org/10.1101/2021.10.23.465573 (2021).
39.Farhy-Tselnicker, I. et al. Activity-dependent modulation of synapse-regulating genes in astrocytes. eLife 10, e70514 (2021).
40.Dove, N. C., Torn, M. S., Hart, S. C. & Taş, N. Metabolic capabilities mute positive response to direct and indirect impacts of warming throughout the soil profile. Nat Commun 12, 2089 (2021).
41.Das, R. et al. An integrated functional and clinical genomics approach reveals genes driving aggressive metastatic prostate cancer. Nat Commun 12, 4601 (2021).
42.Cheung, V. et al. Virally encoded connectivity transgenic overlay RNA sequencing (VECTORseq) defines projection neurons involved in sensorimotor integration. Cell Reports 37, 110131 (2021).
43.Cheng, A. P. et al. Cell-free DNA tissues of origin by methylation profiling reveals significant cell, tissue, and organ-specific injury related to COVID-19 severity. Med 2, 411-422.e5 (2021).
44.Cebrian-Silla, A. et al. Single-cell analysis of the ventricular-subventricular zone reveals signatures of dorsal and ventral adult neurogenesis. eLife 10, e67436 (2021).
45.Bunis, D. G. et al. Single-Cell Mapping of Progressive Fetal-to-Adult Transition in Human Naive T Cells. Cell Reports 34, 108573 (2021).
46.Brown, D. et al. Deep Parallel Characterization of AAV Tropism and AAV-Mediated Transcriptional Changes via Single-Cell RNA Sequencing. Front Immunol 12, 730825 (2021).
47.Biering, S. B. et al. SARS-CoV-2 Spike triggers barrier dysfunction and vascular leak via integrins and TGF-β signaling. bioRxiv 2021.12.10.472112 (2021) doi:10.1101/2021.12.10.472112.
48.Zhao, S. G. et al. The DNA methylation landscape of advanced prostate cancer. Nat Genet 52, 778–789 (2020).
49.Scott, A. D. et al. A Reference Genome Sequence for Giant Sequoia. G3 Genes|Genomes|Genetics 10, 3907–3919 (2020).
50.Sayed, F. A. et al. AD-linked R47H-TREM2 mutation induces disease-enhancing proinflammatory microglial states in mice and humans. 2020.07.24.218719 Preprint at https://doi.org/10.1101/2020.07.24.218719 (2020).
51.Samuel, R. M. et al. Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men. Cell Stem Cell 27, 876-889.e12 (2020).
52.Roth, T. L. et al. Pooled Knockin Targeting for Genome Engineering of Cellular Immunotherapies. Cell 181, 728-744.e21 (2020).
53.Nugent, A. A. et al. TREM2 Regulates Microglial Cholesterol Metabolism upon Chronic Phagocytic Challenge. Neuron 105, 837-854.e9 (2020).
54.Nichols, E. K. et al. Fetal innate immunity contributes to the induction of atypical behaviors in a mouse model of maternal immune activation. 2020.10.09.333815 Preprint at https://doi.org/10.1101/2020.10.09.333815 (2020).
55.Najm, R. et al. In Vivo Chimeric Alzheimer’s Disease Modeling of Apolipoprotein E4 Toxicity in Human Neurons. Cell Reports 32, 107962 (2020).
56.Magill, S. T. et al. Multiplatform genomic profiling and magnetic resonance imaging identify mechanisms underlying intratumor heterogeneity in meningioma. Nat Commun 11, 4803 (2020).
57.Hu, K. H. et al. ZipSeq: barcoding for real-time mapping of single cell transcriptomes. Nat Methods 17, 833–843 (2020).
58.Chaturvedi, S. et al. Transcriptional Feedback Disruption Yields Escape-Resistant Antivirals. 464495 Preprint at https://doi.org/10.1101/464495 (2020).
59.Naguib, A. et al. SUPT4H1 Depletion Leads to a Global Reduction in RNA. Cell Reports 26, 45-53.e4 (2019).
60.Fossi, M., Amundson, K., Kuppu, S., Britt, A. & Comai, L. Regeneration of Solanum tuberosum Plants from Protoplasts Induces Widespread Genome Instability. Plant Physiology 180, 78–86 (2019).
61.Calderon, D. et al. Landscape of stimulation-responsive chromatin across diverse human immune cells. Nat Genet 51, 1494–1505 (2019).
